46 TOXINES AND ANTITOXINES. 



x c.c. of poison ) ^00 

 (100 lethal doses) / + 200 L ' 



x c.c. of poison + ^^. = toxone activity 



x c.c. of poison + . = toxone activity 



99 

 x c.c. of poison + ^Q = 1 toxine activity 



(1 lethal dose) 

 x c.c. of poison + r = 30 lethal doses 



x c.c. of poison + -^-^ = 90 lethal doses, 



and so on. 



The "Spectrum" (EHRLICH) of this simplest conceivable poison 

 may be thus represented 



O 10 ZO 3O 40 50 60 1O 8O OO WO J5O 2OO 



Fig. 1. "Spectrum" of a Fresh Poison. 



But the conditions would certainly never be as simple as these. 

 For, in the first place, the toxines themselves are not uniform in 

 their affinity (to which point we shall have occcasion to return), 

 and, in the second place, they very soon form protoxoids, which 

 alter the curve. For instance, take the following series of 

 values : 



200 

 x poison + ^r = 



180 

 x poison + ^ = tree toxone 



160 

 x poison + --Q = free toxone 



