TOXINE OF FATIGUE. 245 



serum still retains its toxic power after removal by means of 

 specific combinations of the receptors adapted to the corpuscles 

 of the blood. 



Toxine of Fatigue. 



An apparently true toxine has been separated from the muscles 

 of over-fatigued mammalia by WEICHART, 1 who prepared an ex- 

 tract from them under the strictest aseptic precautions. In 

 small doses the toxine has an immunising effect, but in large 

 doses is fatal. It produces a true antitoxine on immunisation. 



1 Weichart, " t)ber Ermiidungs toxin, I. and II.," Munch, med. Woch., 

 1904, No. 1, et seq. 



