MALARIA 8i 



ALTERATIONS IN INFECTED BLOOD CORPUSCLES. 



Q. The red blood corpuscles are little discoloured, and are not 



materially altered in size ; some appear smaller. 

 T. The red corpuscles are often hypertrophied and have lost 

 colour, it may be completely. Schijfifner's dots in deeply 

 stained specimens. 

 S-T. The red blood corpuscles shrink frequently ; they are dark, 

 or may be perfectly colourless. 



RELATIVE NUMBER OF PARASITES SEEN IN PERIPHERAL 

 AND VISCERAL BLOOD. 



Q. Parasites seen in peripheral circulation throughout the whole 

 cycle, and in as great numbers as in visceral blood. 



T. Parasites seen in peripheral blood throughout the whole 



cycle, but not in such large numbers in visceral blood. 



S-T. An enormously greater number of parasites present in 



internal organs as compared with peripheral blood. The 



latter part of the cycle takes place in internal organs only. 



INFLUENCE OF QUININE. 



Q. Causes disappearance of parasites readily. 

 T. Ditto. 

 S-T. Causes disappearance of parasites less readily. 



LIABILITY OF RECURRENCE OF PARASITE AFTER LEAVING 

 INFECTIVE REGIONS. 



Q. Liability persists for a very long period. 

 T. Liability persists for a long period. 

 S-T. After a few months less liability to recurrence. 



THE MOSQUITO. 



It does not follow that if there are Anophelin^e that there is malarial 

 fever, e.g., England, Epping Forest in particular, harbours many of 

 these mosquitoes, but there is no malaria in consequence because the 

 parasite is absent. Again, if there are none of these mosquitoes there 

 cannot be any new cases of malaria if the parasite is brought in bv 

 carriers. 



If there is an attack of malarial fever where there are no mosquitoes 

 it is because the patient has been previously bitten elsewhere. 



For example, cases have arisen after weeks at sea owing to the 

 climatic changes reducing the resistance of the patient and giving the 

 parasites, lying in the spleen probabl}-, a new opportunity to do 

 mischief. 



Where mosquitoes exist the temperature must be favourable for rhe 

 6 



