MALARIA 



Cerebrospinal, 

 Comatose, 

 Hyperpyrexia, 

 Delirious, 

 Tetanic, 

 Eclamptic, 

 Meningitic, 

 Hemiplegic, 

 Amblyopic, 

 Bulbar, 

 Cerebellar. 

 Chronic Malaria. 



Cachexia. 



CLINICAL VARIETIES. 



Sitnple Quartan Fever (Benign). 

 The parasite is P. malariag. 

 Its cycle is seventy-two hours. 



91 



Quartan fever. 



At first the parasite is a small, round, clear speck in the invaded 

 red cell. Its amoeboid movement is feeble. 



When it becomes pigmented all amoeboid movement ceases. 



The hasmozoin it carries is large in amount, coarse in grain, and 

 is seen as short rods. 



The segmented or mature parasite has eight to ten merozoites, 

 symmetrically arranged " daisy " fashion around the block of black 

 haemozoin. 



A shining nucleolus can be seen readily in the centre of each pear- 

 shaped segment. 



The gametocyte or sexual form is a spherical pigmented body like 

 an ordinary parasite that has escaped whole from the red cell. 



The hcemozoin granules may show very active amoeboid movement. 



The enclosing red cell is not enlarged. 



When mature the parasite completely fills the cell, often without 

 any ring of haemoglobin, but as red cells vary in size in these fevers, 

 a quartan parasite in a large erythrocyte may resemble a tertian parasite 

 in certain stages of its growth. 



