Mott. 



Plate D. 



Fig. I. 

 Thread - like 

 bodies and gran- 

 u 1 e s deeply 

 stained, seen in 

 section of lym- 

 phatic gland, 

 probably altered 

 and degenerated 

 trypanosomes. 

 Magnification 

 1 ,000. 



Fig. 2. 

 Trypanosome in a lymphatic gland 

 section amidst disintegrated cell products. 

 Figs. 3 and 4 (Plate IV.), and figs, i and 2 

 (Plate v.), are drawings made from the 

 same sections, 5 M in thickness, stained 

 with Leishman's stain and prepared from 

 an enlarged cervical gland removed during 

 life from a case (Bara 

 Risgallah) of trypano- 

 some fever, before sym- 

 ptoms of sleeping sickness 

 had occurred. Magnifi- 

 cation 1,000. 



Fig. 3. 

 'Trypanosoma 

 Gainbiense i n 

 , smear of fresh 

 gland juice, 

 several 1 y m- 

 phocytes, micro- 

 nuclei. Magnifi- 

 cation 1,000. 



Fig. 4. 

 Section of 

 lymphatic gland 

 from a recently 

 fatal case of 

 sleeping sickness 

 in a European. 

 The glands in 

 tliis case were 

 not much en- 

 larged. There is 

 a very marked 

 proliferation of 

 the endothelial 

 nuclei. Magnifi- 

 cation 500. 



Fig. s. 

 Proliferation of the connective tissue cells of the 

 reticulum of a lymph sinus; marked proliferation 

 of the nuclei of the endothelial cells seen. This 

 chronic change closely accords with the change 

 observed in the perivascular lymph spaces of the 

 central nervous system. Magnification 500. 



Fig. 6. 

 Various granules and products of cell (and try- 

 panosome ?) degeneration seen in the perivascular 

 infiltration of the central nervous system in 

 sleeping sickness. Magnification 1,000. 



A.Kelley- del. 



Baie &.Daai«l»soa, J>^ lith 



