140 



DISEASES DUE TO PROTOZOA 



The local irritation of the tsetse bite may be so slight as not to be 

 observed, but in some there is a raised itching patch which may last 

 for several days. 



SUMMARY OF SYMPTOMS. 



To aid the memory these may be summarized as follows : Poly- 

 adenitis, fever, erytiiema, paresis, tachycardia, somnolence, cedema, 

 enlarged spleen, anaemia, headache, epileptiform fits, tremors, 

 change of character, itching, hypera^sthesia, incontinence of f^ces 

 and urine, enlarged liver, eye symptoms, delusions, insomnia, 

 vomiting, melancholia, epistaxis, feet pains, paresis of lower ex- 

 tremities, dermatographia, painful swelling of ankle, sexual impotence, 

 hemiplegia, giddiness, deafness, loss of hair, phlebitis, facial paralysis 

 and orchitis. 



FEBRILE OR GLANDULAR STAGE. 



This stage is known to some as the Trypanosome Fever Stage. 



The manifestations in Europeans are much more frequent than in 

 natives, and may be considered as follows : — 



Fever. — There are attacks of fever unaffected by quinine, lasting 

 for about one week and recurring at intervals, or the fever may not 

 recur, or may be so slight as not to be noticed, or it may be taken as 

 a " touch of malaria." 



Chart I, 1909, Onset of disease and marked temporary effect of soamin in the 



second week. 



The pulse-rate and respirations are increased. The pulse-rate may 

 be very rapid during the febrile attacks and during the apyrexial period 

 also. The spleen and liver enlarge, but it is difficult to exclude malaria. 



Neuralgic pains and headaches are common. 



Erythematous Eruptions. — Pinkish patches, irregular in position 

 and outline clear in the centre, mav be horseshoe shape or circular; 



