72 NUJIBER OF FOLLICLES. 



intestine, as they appeared in Dr. Boehm.* D, Is the natural 

 size of the piece magnified. They are arranged side by side 

 perpendicularly in the membrane, their closed or caecal bases 

 resting upon the subjacent cellular tunic of the intestines, 

 as seen at 2, which represents a perpendicular cut through the 

 mucous membrane, down to the cellular coat. 3, Is the surface 

 of the cellular coat, from which the mucous membrane has been 

 removed, showing the pits or depressions in which the bases of 

 the follicles are lodged. 1, Is the free surface of the mucous 

 membrane, showing the openings of the follicles which are 

 believed to be the same as the orifices of Lieberkuhn. In the 

 stomach, the cryptas or follicles alone are said to exist, except at 

 the curvatures, where a few of Brunner's glands are met 

 with ; yet in a child dead from summer cholera, the follicles 

 were so enlarged or hypertrophied that I could distinctly count 

 with the naked eye, in a square inch on the sides of the 

 stomach near the pylorus, a hundred and twenty-five opaque 

 bodies below the membrane, which presented all the usual 

 characteristics of the glands of Brunner in the small intestines. 

 In the same subject, the glands of Brunner, (duodenal mucous 

 glands,) were much enlarged ; and in the same extent of 

 surface, I counted without a glass, a hundred and seventeen 

 in the duodenum, ninety-five in the upper portion of the jeju- 

 num, and thirty-five at the commencement of the ileum. 

 Dr. Horner,! who is justly distinguished as an anatomical 

 discoverer, has made, with the assistance of Dr. Goddard, the 

 size and number of these follicles, the subject of attentive mi- 

 croscopical examination. He has found them to vary in size 

 in the stomach from the /gth to the ^Ijjth part of an inch in 



* De Structura Glandulorum Intestinorum. Berl. 1836. 



f Special and General Anatomy, vol. 2, p. 40, fourth edition. 



— To Professor Horner, Dr. Boehm and Dr. Boyd, the science is much 

 indebted for a more minute knowledge of the structure of the mucous mem- 

 brane that it previously possessed. Professor Horner's interesting researches 

 were made upon the viscera of subjects who had died of cholera asphyxia, and 

 were published in the May and August numbers of the Americ. Jour, of the 

 Med. Sciences for 1835. — Dr. Boehm's observations were also made on the 

 choleric mucous membrane, and were published at Berlin in 1835; — Dr. Boyd's 

 at Edinburgh, in 1836. From the respective dates it would seem that Dr. 

 Horner led the way in this discovery. — p. 



