With regard to the ability of the non-nucleated cell 

 to secrete, there are some interesting observations upon 

 Ameba proteus. In normal movement as seen upon a glass 

 slide, this organism is attached to the bottom and can 

 thus move from place to place. This ability to stick to 

 the bottom, as well as to stick to food particles, seems 

 to depend upon a secretion which is present upon the sur- 

 face of Ameba. Without this secretion the ameba is not able 

 to move from place to place, but can only stretch out pseud- 

 opods in different directions. That the production of this 

 secretion is in some way dependent upon the presence of 

 the nucleus is shovm by the fact that the secretion is 

 absent shortly after the removal of the nucleus, as shown 

 by Hofer. 



Further evidence upon the question of the ability of 

 the enucleated cell to produce secretions is found in ex- 

 periments upon digestion. Hofer, Gtr^lc, and others have 

 observed more or less normal digestion of food particles 

 535^H after removal of the nucleus: but observations made 

 upon the digestion of particles ingested before enucleation, 

 and to which the digestive secretions have already been 

 added, are little more to the point than observations 

 made upon digestion in a test tube. Some crucial experi- 

 ments v/ere performed by Hofer, hcvever. Hofer removed the 



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