63 



While the thick, irregular rods continue to lose their 

 capacity for tcUcine up stains, there appear) scattered 

 throughout the nuclear cavity^ but riiciinly ne;\r tlie periplijry 

 a niunber of small spherical "bodies (figS- 12^) . In ifi£i,n2'- 

 instances, 14 of these bodies v/ere countod; less frequently 



d.TlJ often tKe- i-vu-mber a,f[>e^re3 to la 



only 13 v/ere to be seen;, in the lattor e vent s — one of the 



o-reate-r tKa^n tMs. 



jp. iiulca ia luZ-.-'ccr tjian the rost, and is probably to be 

 con - sidered ac roiiroGonting tv.o of tho amallcr bodi e s — (rfirg, 

 iS^ , After these bodies are formed, there may be no other 

 trace of nucleolar ros.tei^ial in the nuclear cavity (fig/-?^) 

 or the acliroiaatic portion of the nucleolus may be represent- 

 ed by t».o or tliree faintly staining bodies of irregular 

 outline lying neix the centre of the nucleeir cavity (fig,7-2^^y* 

 This is the stage of prophase and the siiiall bodies scat- 

 tered through the nuclear cavity are the chromosomes. 



ITot all the nucleolus goes to form tiie chromosomes . 

 As already mentioned, part of the nucleola,r substance pas- 

 ses out of the nucleus and becomes dei^osited in the vac- 

 uolar c^/'toplasm, and part may remain in the nuclear cavity^ 

 where it forms irregular riU.snes. The part remfj.ining in 

 the nucleus ultimately disappecirs in the cytoplasm after 

 the nuclear membrane is dissolved. 



