38" THE VENOMS OF CERTAIN T II A N A T O P H I D E M. 



The delay in the occurrence of death in this experiment was considerable, and 

 that this was due to the action of the iodine on the venom is rendered probable 

 by the results of the preceding experiments with iodine and by the following 

 experiment with the potassic iodide. 



Potassic Iodide. This salt does not seem to exert any influence upon the activity 

 of venom. 



Experiment. Dissolved 0.015 gram dried venom of the Crotalus adamanteus in 

 1 c. c. saturated solution of potassic iodine. 



4:31. Injected into the breast of a pigeon. 

 4:40. Down. 

 4:45. Dead. 



Potassic Bichromate. Experiment. Dissolved 0.03 gram dried Crotalus ada- 

 manteus venom in 1 c. c. distilled water and added 0.01 gram potassic bichromate. 



4:14. Injected into the breast of a pigeon. 



4:20. Down. 



4:25. Convulsions followed by death. 



Experiment. Dissolved 0.004 gram dried venom in 0.5 c. c. distilled water and 

 added 0.03 gram potassic bichromate dissolved in 0.33 distilled water, which pro- 

 duced a dense coagulum. 



3:38. Injected into the breast muscles of a pigeon. 

 4:05. Dead. 



Potassic Permanganate. Experiment. Dissolved 0.03 gram dried Crotalus 

 adamanteus venom in 0.5 c. c. distilled water and added 0.06 gram permanganate 

 in 0.5 c. c. distilled water. This formed a very cloudy solution. 



5:27. Injected into the breast of a pigeon. Death occurred within forty-eight hours. 



Experiment. The same, using 0.015 gram of the permanganate. At the end 

 of the second day no poisonous effects from the venom. The parts where the injec- 

 tion was made look as though they would slough. 



Experiment. The same, using 0.005 gram of the permanganate. The solution 

 formed is a dark wine color. 



4:37. Injected into the breast of a pigeon without effect. 



Experiment. The same, using 0.0038 gram of permanganate. 

 4:26. Injected as above. 

 4:42. Down. 

 4:45. Dead. 



Experiment. The same, using 0.0025 gram of permanganate. 



3:57. Injected as above. 

 4:06. Down. 

 4:10. Dead. 



In another experiment, the mixture was injected into the femoral vein of a 

 rabbit, using 0.005 gram permanganate. The animal lived, and at the end of the 

 second day was apparently unaffected. 



In one observation made with the venom of the Crotalus horridus 0.015 gram 

 of venom was dissolved in 0.5 c. c. distilled water, to which was afterwards added 

 0.008 gram of the permanganate. After standing for twenty-four hours the 



