THE EFFECTS OF VENOM. 47 



is the globulins which most rapidly alter blood and vessels, and by a mechanism 

 hereinafter to be described cause ecchymoses. Yet are the peptones not without 

 this toxic capacity, as is seen in some of the above observations. Clearly, however, 

 boiling impairs the activity of Crotaline peptones, as it does that of like constitu- 

 ents of Cobra poison. It will have been seen that none of these direct experiments 

 on serous tissues were made with pure or boiled Cobra venom. It is desirable that 

 this should be done, and especially with fresh venom. In another portion of this 

 paper there are some relative studies of the power of dried Cobra and Rattlesnake 

 venoms to cause local hemorrhages from the peritoneum. In the former work of 

 Dr. Mitchell, and in that of Fayrer and Brunton, are sufficient studies of the ab- 

 sorbing power of rectal and pulmonary surfaces and of the eye. 



