THE ACTION OF VENOMS UPON A K T E ill A L PRESSURE. 95 



Experiment No. 25. 



Time : 



Normal 



Experiment No. 26. 



Normal 



Experiment No. 27. 



Normal 



Time: 

 min. sec. 





 10 

 20 



1 00 



2 00 

 4 00 



10 

 15 



REMARKS. 



Injected intravenously 0.003 gram dried Cobra venom dis- 

 solved in 1 c. c. distilled water with a few crystals of sodic 

 chloride and filtered. 



Clot formed in canula. Animal killed. 



REMARKS. 



Injected intravenously O.OOC gram dried Cobra venom pre- 

 pared as in the foregoing experiment. 



Convulsive movements; asphyxia; respiration ceased in three 

 minutes. 



Pressure REMARKS, 



m. m. 



130 Injected intravenously 0.003 gram dried Cobra venom dis- 

 . . . solved in 1 c. c. distilled water. 



130 

 118 

 118 

 115 

 . . . Clot in canula. 



Dead from asphyxia 



The Action of Pure Venoms on the Blood Pressure of Animals in which the 

 Cervical Spinal Cord had been Divided. Upon section of the spinal cord in the 

 upper cervical region, by which the influence of the vaso-motor centres in the 

 medulla is practically destroyed, the primary fall of pressure from venom is gener- 

 ally very slight, and after this diminution there is a secondary rise which may go 

 above the normal. In one experiment with Crotalus adamanteus venom there 

 was a rise of pressure for a moment at the time of injection ; in one experiment 

 with Crotalus horridus, in which a somewhat larger dose was used than in the 

 others, there was a distinct rise of pressure a few seconds after injection, followed 

 by a fall ; and in the experiment with the Cobra the pressure never went below 



