110 



THE VENOMS OF CERTAIN T II AN A T PII I D 



neck and the cord in the middle or upper cervical region (excepting one) were cut. 

 They were all made with the globulins from the Crotalus adamanteus ; one with 

 water-venom-globulin, one with copper-venom-globulin, and two with dialysis-venom- 

 globulin. 



The results of this series of experiments accord with those observed when pure 

 venom was used, and with the preceding experiments with the globulins. The 

 primary fall of pressure is slight, while the tendency to a secondary rise is very 

 marked, since in three of the experiments the pressure rose above the normal. 

 The action of water-venom-globulin on the primary fall was most marked, while in 

 the single experiment made with copper-venom-globulin, in which eight times the 

 quantity was given in two doses, the pressure rose slightly, and continued above 

 normal. When the dose is sufficient to kill, the pressure ultimately gradually 

 declines, accompanied by a feeble pulse. 



In the last experiment with dmlt/sis-venom-glolulin it will be noticed that 

 tremors are accompanied with a rise of pressure during their existence. 



Experiment No. 59. 



Normal 



Time: 

 m In. sec. 



10 



Pressure 



m. m. 



48 



38 



REMARKS. 



Section of cord made below the 6th cervical vertebra. Injected 

 intrav.enously 0.0011 gram ivater-venom-ylobulin from the 

 dried venom of the Crolalus adamanteus. 



Artificial respiration stopped. 



Animal killed by pithing. 



Experiment No. 60. 



Normal 



Time: 

 inin. sec. 



10 

 20 

 40 



1 00 

 3 30 

 5 30 

 7 30 



Pressure 

 m. m. 



29 

 32 

 30 

 32 

 32 

 38 

 40 

 42 



REMARKS. 



Injected intravenously 0.0048 gram copper-venom-globulin 

 from the dried venom of the Crotalus adamanteus. 



