xxxiv INTRODUCTION. 



moving the coagulable lymph from the blood by whipping it 

 with twigs. In the second edition, too, he dwells on the evi- 

 dence of the flat shape of the corpuscles, 1 and omits the vague 

 observations which he had given in the first edition on the effects 

 of neutral salts, and on the fluidity of the blood being preserved 

 by a heat of 96. 



The doctrine of Leeuwenhoek was taught by the first Dr. 

 Monro, at Edinburgh, up to the year 1758; and the first 

 lectures of his son 2 and successor were employed in refuting 

 this system, and in proving the distinction between the different 

 parts of the blood. 



Dr. J. M. Butt 3 followed Malpighi in the description of the 

 blood-clot, adding that Senac aptly named the fibrous part 

 coagulable lymph, which also forms the part commonly called 

 the inflammatory crust. Yet Dr. Butt says the serum is com- 

 posed of coagulable lymph, watery fluid, and saline matter. 

 He stated that if serum be exposed to a heat of 150, it con- 

 cretes into an uniform mass, from which exudes, after it is cut 

 into thin slices, a watery saline liquor, called serosity by Senac. 

 I have not met with an expression exactly equivalent to coagu- 

 lable lymph in Senac' s work, though, as I have already noticed, 

 he mentions coagulated lymph, and lymph which coagulates of 

 itself; and he used the word serosity merely for the serum. 

 Sir John Pringle 4 mentioned, in a note to a paper read before 

 the Royal Society, February 13, 1752, that the inflammatory 

 crust is the same part of the blood as that called by M. de Senac 

 the white matter which coagulates of itself. 



Gaubius 5 distinguished the three proximate constituents of 

 the blood. He described the fibre as forming the basis of the 

 clot, and as exceedingly different from the red part and from the 

 serum, especially in the power of coagulating spontaneously. 

 The inflammatory diathesis he attributed to a mucus generated 

 in the serum and coagulating in the manner of the fibre ; and 



1 Traite du Coeur, 2d edit. torn, ii, p. 276-77. 



2 Essays and Heads of Lectures, &c., and Memoir of Dr. Alexander Monro secuudus, 

 by his Son and Successor, p. xiv, 8vo, Edinburgh, 1840. 



3 De Spontanea Sanguinis Separatione, pp. 504, 514, 521, 510, 4to, Edinb. 1760; 

 in Sandifort. Thesaur. Dissert. 4to, Roterodami, 1769. 



4 On the Diseases of the Army, 5th edit. App. p. Ixxiv, 4to, London, 1765. 



5 Institutions Pathologise Medicinalis, $$ 339, 344, 340, 361, 367, 280, 345-47, 

 8vo, Leid. Bat. 1758. 



