CLINICAL CASES 379 



success when these experiments were first undertaken 

 six months ago. They were undertaken more with a 

 view to see what the effect of globin in this way was 

 than with the object of obtaining a cure of the tumours 

 from which the patients were suffering. But, as will 

 be seen from the description of the treatment, the 

 results have exceeded our anticipations. Unfortunately, 

 since we did not expect any beneficial results, the cases 

 were not the most suitable which could have been 

 chosen, for both of them had "internal" growths which 

 were inaccessible, and therefore we were at that time 

 unable to prove conclusively that they were suffering 

 from carcinoma. 



The first patient 1 to whom the serum was adminis- 

 tered was a woman (I. G.) aged 45 (admitted to the 

 hospital on January 11, 1910), whose left breast had 

 been removed in November, 1907, for a carcinomatous 

 growth. She remained well until April, 1909, when she 

 began to suffer from a severe pain in the region of the 

 sacrum and left hip. She stated that this pain had 

 since then become worse and that no treatment had 

 relieved it. The left lower extremity from the hip to 

 the ankle had for long been swollen and cedematous, 

 and there had been swelling also in the abdomen. 

 Any movement of the limb caused severe pain, and 

 she had great difficulty in turning herself in 

 bed. The patient was too ill to be weighed at the 

 time of her admission, but she was manifestly wasted, 



1 These two cases were treated under the supervision of Dr. Macalister, 

 who has kindly written these descriptions of them. 



