380 



was anaemic, and had a worn expression. On exami- 

 nation there was manifest swelling on palpation in 

 the left iliac region, and, examined per rectum under 

 chloroform, a hard swelling could be felt attached to 

 the anterior surface of the sacrum and sweeping round 

 the wall of the pelvis towards the left side. An X-ray 

 photograph confirmed the involvement of the sacrum. 

 After treating her with mercurial inunctions and other 

 remedies for a month without benefit, the defibrinated- 

 blood injections were commenced on February 21, 1910. 

 At first they were given in the evening, and were often 

 followed by sickness and sometimes by actual vomiting ; 

 it was found that there was less disturbance when the 

 injections were given in the mornings. 1 The sickness 

 was so troublesome at first that the treatment had to 

 be abandoned on March 3, and it was not until 

 March 20 that it was again started and continued 

 uninterruptedly. Gradually her pains improved, and 

 the swelling in the leg diminished. (No opiates were 

 needed after March 29.) On April 20 she could stand 

 with very little pain, and she was weighed for the first 

 time (109 lb.). Improvement continued week by 

 week, she became bright and younger-looking, and 

 on June 8 she weighed 115 lb. No pain could be 

 elicited on pressure over the left iliac region, and the 

 tumour seemed smaller. She maintained her weight, 

 with some variation, for some weeks, and was able to 

 walk about the ward without assistance until July 21, 



1 In these cases treated with rectal injections of defibrinated blood 

 there has been sickness following the injection, but this has passed off 

 as the treatment has been persevered with. 



