390 PREVENTION OF PROLIFERATION 



I considered that the opportunity had now ar- 

 rived to try the crucial test. A mixture was m.-idt- 

 of a solution containing five parts of globin and 

 one part of choline. It was evaporated to dryness 

 with aseptic precautions, and the dried mixture sealed 

 up in a glass tube. A minute portion of the edge of 

 the treated ulcer, from which the last section had been 

 taken, was now r scarified and small pieces of the 

 dried aseptic mixture of globin and choline directly 

 applied to it. In 48 hours a conical excrescence 

 appeared at the seat of application. A section has 

 been cut from it, and the photomicrograph shows 

 apparently new malignant cells to be infiltrating the 

 granulation tissue once more in an abnormal manner 

 similar in appearance to the original infiltration of the 

 ulcer (figs. 124, 125). 



Now, this test is by no means conclusive. I can- 

 not assert that there were no original carcinomatous 

 cells at the seat of application, and that I was 

 not merely producing augmented proliferation of 

 these cancer-cells. The section may be fallacious 

 owing to the "error of random sampling," for be- 

 cause no abnormal cells appear in samples removed 

 from the treated site it does not prove that none 

 exist in the neighbourhood. Still, the experiment is 

 interesting, because the conical excrescence only 

 appeared at the site of the application of the com- 

 bined auxetic and the alkaloid of putrefaction, the 

 rest of the ulcer remaining in statu quo. 



This test will have to be repeated many times 

 before one can speak conclusively on the subject; 



