278 THE ADRENAL SYSTEM AND VASOMOTOR FUNCTIONS. 



nection: i.e., to illustrate the independence of the process from 

 the nerve-centers, when sweating is induced. This physiologist 

 cut the sciatic nerve of a young cat, then injected pilocarpine. 

 Sweating from the four paws occurred, the operation having 

 in no way interfered with the result. We have seen that 

 removal of the stellate ganglion in cats was followed by loss 

 of vascular tonicity in the head-supply, but it likewise does so 

 in the upper extremities. We also know that the adrenal on 

 the normal side, and probably collateral nerves connected with 

 that on the operated side, compensate, in a measure, for the 

 primarily isolated organ. Onuf and Collins removed the left 

 stellate ganglion of a cat and three months later injected pilo- 

 carpine. About ten minutes after the injection both front 

 paws were sweating; the left, however, less than the right; 

 six hours later all paws were still somewhat moist. In another 

 animal "instillation of a few drops of a 2-per-cent. solution of 

 pilocarpine into each eye produced sweating of all paws, ap- 

 parently no less of the forepaw of the side (right) on which 

 the stellate ganglion had been removed four and one-half 

 months previously." We are evidently dealing with a general 

 functional mechanism, the most active part of which is as- 

 cribable to the adrenals. 



Another side of the question may be introduced by quot- 

 ing a passage from the paragraph immediately after that just 

 referred to. Alluding to the first cat (No. 2 in their series), 

 from which the left stellate ganglion had been removed, Onuf 

 and Collins say: "But yet we had to note the paradoxical 

 fact that, when, on a later occasion, we began the etherization 

 of cat No. 2 in order to perform another operation, the strug- 

 gles of the animal against being etherized produced consider- 

 able sweating of all paws except the left forepaw, which re- 

 mained perfectly dry." We are no longer dealing here with 

 induced diaphoresis, but with the purely physiological form 

 of sweating, that due to excessive muscular activity, and 

 involving primarily, therefore, active participation of the 

 nervous system. In the induced form, on the other hand, 

 sweating was incited inordinately through overaction of the 

 adrenals and through stimulation of the medullary centers. 

 Yet there is also involved in the process much of the same 



