420 INTERNAL SECRETIONS OF PANCREAS AND SPLEEN. 



we find that a slight excess of splenic ferment will serve the 

 physiological process in the pancreas, to supply the intestinal 

 canal, if we grant the vagus even one-tenth of the truly 

 wonderful prerogatives it seems to possess, we can readily as- 

 sume that, by regulating the quantities of either ferment al- 

 lowed to enter the blood-stream, it provides just the excess of 

 splenic ferment in the pancreas to insure perfect function 

 during the digestive process: all features which indicate that 

 trypsin is a constituent of the entire Uood-stream when albuminoids 

 are undergoing digestion in the alimentary channels. 



The far-reaching meaning of all this is suggested in the 

 following deductions: 



1. The cleavage processes to which trypsin submits albumins 

 in the intestinal canal include the preliminary steps of a protective 

 function. 



2. The spleno-pancreatic internal secretion is represented by 

 the trypsin which reaches the portal vein by way of the splenic 

 vein., and which continues in the blood-stream the cleavage processes 

 begun in the intestinal canal. 



8. The main function of the spleno-pancreatic secretion, 

 trypsin, in the blood-stream is to protect the organism from the 

 effects of the toxic derivatives of albuminoid bodies. 



