714 INTERNAL SECRETIONS AND PRESERVATION OF LIFE. 



This recalls our statement (page 440) in respect to the 

 manner in which the heart-muscle is supplied with its myo- 

 sinogen. We then said, referring to the present analysis: 

 "Paradoxical as the statement may seem, we were led to con- 

 clude that the minute granules referred to on page 433" a 

 general outline of the prevailing views concerning the histology 

 of the myocardium, in which the minute pigment-granules, 

 easily seen therein microscopically, are mentioned "were act- 

 ually supplied to the heart through the intermediary of leuco- 

 cytes. These cells were found to migrate from the liver (also 

 through the hepatic veins) to the inferior vena cava, where they 

 meet the adrenal secretion and proceed with it to the right 

 ventricle." 



We can now readily understand how the granules of the 

 neutrophiles are supplied to the muscle-fibers by quoting an- 

 other of our own statements (page 434) concerning the dis- 

 tribution of fluids in the intimate structure of the heart: 

 "Fluids can penetrate through the maze of cellular tissue to 

 the bare muscular fibers; the sheaths that include the columns 

 or chains of muscular bundles afford a peculiar system of cana- 

 lization through which the liquids can easily gain access to them. 

 The canals the lacunae of Henle are the intervals between 

 the columns of secondary bundles, or their sheaths, rather, 

 which are placed in longitudinal apposition. Schweigger-Seidel 

 and Kanvier having observed that interstitial injections of col- 

 ored substances penetrated the lymphatic vessels; the lacunae 

 have been considered as adjuncts, or extensions, of the latter." 

 In this sense, therefore, the Thebesian channels are adjuncts of 

 the lymphatic system, for it is through their intermediary that 

 the lacunae of Henle are supplied with myosinogen granules and 

 a feature we wish to emphasize their nutritional peptones 

 and their fibrinogen. All of these jointly supply the heart with 

 its working energy, when acted upon by the oxidizing substance 

 of the blood-stream. 



The bulk of the venous blood which enters the heart is 

 sent, we have seen, along with its adrenal secretion and its leu- 

 cocytes neutrophile and eosinophile to the lungs, Virchow, 

 Friedreich, Leyden, Cohnheim, Wagner, Lenhartz, and other 

 investigators having found them in the sputum, and histology 



