IMMUNIZING MEDICATION. 76D 



hand, Baccelli's method is alone resorted to, and the drug be 

 administered in doses no larger than those he recommends, we 

 feel confident, if our views are' sound, that the results obtained 

 in all countries will but coincide with his own. Suffering may 

 require the use of morphine; fortunately, this agent also stimu- 

 lates the adrenal system, when given in therapeutic doses. 



But Baccelli's clinical experience with tetanus when coup- 

 led with our views seems to us to suggest a far-reaching appli- 

 cation of such energetic adrenal stimulation. Indeed, we have 

 fully emphasized throughout this work the kinship between all 

 conditions attended with convulsions. The main disorders which 

 may be classed as such are: epilepsy (other than purely traumatic), 

 puerperal and infantile convulsions, and hydrophobia. Though 

 the latter disease is the only one of the three which presents 

 a direct analogy to tetanus as regards primary cause, i.e., an 

 exogenous virus, the convulsion-producing factor is neverthe- 

 less the same in all: i.e., an accumulation in the blood-stream 

 of toxic waste-products incident upon adrenal insufficiency. It 

 follows, therefore, that a treatment similar to that which Bac- 

 celli employs in tetanus should also prove effective in all these 

 affections, since it becomes evident that carbolic acid is able 

 not only to counteract the insufficiency of the adrenal system, 

 and cause the latter to resume its normal functional activity, 

 but also to raise this activity ~beyond the normal, flood the cir- 

 culation with its defensive and offensive weapons, and convert 

 the enemies of the organism into benign elements. 



Arsenic is another agent that has been found of great 

 value in malaria. Boudin, 101 one of the pioneers in its use as 

 a prophylactic agency, introduces a suggestive remark which 

 acquires considerable weight when the fact that his experience 

 was acquired while surgeon-general of the French armies in the 

 field during the Algerian campaigns: "I am assured by suc- 

 cessive trials, which have been repeated with similar results by 

 many others, that arsenous acid preserves, in the somewhat 

 microscopical doses of 1 / 100 grain, all its medicinal energy, not 

 only in marsh-fevers, but also in a multitude of other diseases. 

 Further, I have obtained from 1 / 100 grain of this remedy the 



101 Boudin: "Trait6 des FiSvres Intermittentes," Paris, 1842. 



