1 66 THE KINGDOM OF MAN 



weeks. The experiments by which Colonel Bruce demon- 

 strated this relationship of tsetze-fly, trypanosome parasite, 

 wild big game, and domesticated animals, were universally 

 regarded as masterly both in conception and execution, 

 and absolutely conclusive. 



The committee of the Royal Society came to the 

 conclusion that the thing to be done was to get 

 Colonel Bruce to consent to proceed to Uganda, and 

 to recommend the Foreign Office to obtain from 

 the War Office the temporary detachment of 

 Colonel Bruce for this service. Accordingly Colonel 

 Bruce arrived in Uganda in the middle of March, 

 1903. Dr. Low and Dr. Christy had already departed, 

 but Dr. Castellani was still at Entebbe engaged in the study 

 of his streptococcus. He mentioned to Colonel Bruce on 

 his arrival that he had on more than one occasion seen 

 a trypanosome in the cerebro-spinal fluid of negroes 

 suffering from sleeping sickness ; but, inasmuch as Dutton 

 'on the West Coast and Hodges in Uganda had described 

 a trypanosome as an occasional parasite in human blood, 

 he had not considered its occurrence in sleeping-sickness 

 patients as of any more significance than is the occurrence 

 of Filar ia perstans. Castellani regarded the trypanosome, 

 like the filaria, as a mere accidental concomitant of 

 sleeping sickness, the cause of which he considered to be 

 the bacterial streptococcus which he had so frequently 

 found to be present. 



Naturally enough, Bruce was impressed by the fact 

 that trypanosomes, of the deadly nature of which he had 

 had ample experience, had been found, even once, in the 

 cerebro-spinal fluid of sleeping-sickness patients ; and he 

 immediately set to work to make a thorough search for 

 this parasite in all the cases of sleeping sickness ; then 

 under observation at Entebbe. He generously allowed 



