X CONTENTS 



CHAPTER III. 



EVOLUTION OP THE INFECTIOUS DISEASES. 



(1) Diphtheria. Action of Toxin on the Tissues. Fixation 



"en Surcharge" of Toxin. Experiments. Properties 

 of Mixtures of Toxin with Antitoxin. Immunity. 

 Cure by Antitoxin. 



(2) Tuberculosis. Action of Tuberculin. Action of Bacter- 

 ial Bodies. Antituberculin and Antibacillin. The Sur- 

 charge of the Organism by Antibodies Causes Patho- 

 logical Manifestations. Auto-reinfections. 



(3) Typhoid and Paratyphoid Fevers. Cholera. Mechanism 

 of Gastro-intestinal Infections. Formation and Action 

 of Precipitating Antibodies. Exotoxins and Endotoxins. 

 Nature of the Pathological Symptoms in the Period of 

 Disease. Mechanism of Spontaneous Cure. Patho- 

 genicity of Alimentary Poisoning by Paratyphoid. 

 Pathogenicity and Nature of Cholera Crisis . . . 45-73 



CHAPTER IV. 



MECHANISM OF INFECTION. INFECTION OR CONTAGION. VIRULENCE. 

 IMMUNITY. REFRACTORY STATE. 



Means of Adaptation of Bacteria to the Interior of the 

 Organism. Origin of the Affinities between the Anti- 

 gens and the Normal Antibodies. Immunity and 

 Reciprocal Anaphylaxis of Infecting Bacteria and of 

 Infected Organisms. Experiments on the Pathogenesis 

 of Paratyphoids and of Rat Anthrax .... 74-81 



CHAPTER V. 



IMMUNITY AND ANAPHYLAXIS. 



Formation of Immunizing and Anaphylactic Antibodies. 

 Reason for the Existence of Anaphylaxis. Nature of 

 the Antigens. Colloids. Constitution and Physico- 

 chemical Properties of Particles. Combinations of 

 Colloids with Salts in Varying Proportions. Action 

 and Nature of Antibodies . 82-108 



