INFLUENCE OF CENTRAL NERVOUS SYSTEM 113 



SUMMARY. If the facts actually known hardly permit 

 us to understand the nature and the mechanism of the 

 influences which different varieties of excitations of nerve 

 centers exert on the reactions between antigens and anti- 

 bodies we may assume that these reactions are probably 

 never purely local, that they are always influenced by 

 nervous states, conscious or subconscious, direct or reflex. 

 The suggestion which we may draw from this is to investi- 

 gate the action of different anesthetics, hypnotics and 

 narcotics or infections, especially in the severe cases with 

 nervous disturbances. 



