CASE REPORTS 167 



no guide which could have suggested the choice of one germ 

 rather than of another, we chose, to begin with, the germs 

 whose cultivation was easiest and simplest: surface growths 

 on gelatin slants, therefore, the commonest aerobes. 



In order to recognize their morphologic characters, their 

 biochemical and pathogenic properties, each germ was 

 isolated in a pure culture, then cultivated in different media, 

 and lastly injected, either mixed or separately, into mice. 



It is to be noted here at once that the mice so treated never 

 contracted a fatally infectious disease in spite of the relatively 

 strong doses (0.1 c.c. of a twenty-four-hour broth culture) . 

 We were thus handling only innocuous germs. 



Another patient was treated with a heterogeneous prepara- 

 tion and encouraged by the result obtained we entrusted the 

 same material to Dr. Labonnette for the treatment of a 

 serious case of eczema. 



Observation 4- l ~ This patient had a long history of gastro- 

 intestinal disturbances with abdominal and rheumatic pain 

 at various times. In April, 1919, a seborrheic eczema of the 

 trunk and scalp plus an oozing eczema of the perineum and 

 scrotum appeared. The patient was given dead heterogeneous 

 bacteria of which he took by mouth 2 mg. as an emulsion 

 daily. Disappearance of the pains and of the eczema was 

 almost instantaneous. 



Observation 5. Another patient was treated in a similar 

 manner except that the development of pustules indicated 

 additional treatment with a staphylococcic autovaccine 

 obtained by culture of these pustules which was given. 



Observations 6 and 7. Two cases of psoriasis were also 

 much relieved by the injection of entero-antigens. In one of 

 these, a second course of treatment was begun ten days after 

 the end of the first course but the local reactions were not 

 more severe than the first the patient was therefore not 

 sensitized by the first course. 



Case 7 received during his psoriasis and independently the 

 Pasteur treatment for rabies as a sequel to which the skin 

 lesions healed. 



1 Observation 3 omitted in English translation. 



