170 ANTI-ANAPHYLACTIC TREATMENT OF DISEASES 



doses of the different antigens which it was necessary to use 

 to obtain similar results. 



The total quantity of bacterial bodies used in from twenty 

 to sixty injections, varied from 0.4 mg. to 2 mg., while the 

 total quantity of marrow injected in fifteen injections and 

 of luargol injected in ten injections can be estimated at from 

 1.5 to 2 gr., that is to say, a quantity a thousand times 

 greater than that of the bacteria. 



The same can be said of the action of the anaerobic bacillus 

 (Observation 6) which seems to be at least 100 times as 

 pronounced as that of all other bacteria put together. 



The antigenic action on psoriatic lesions could thus be 

 explained as follows : 



1. Recovery is determined by reactions in the organism 

 caused by antigens. 



2. These reactions are all of the same kind, or at least 

 very similar. 



3. The same results can be obtained by different antigens 

 in very different doses, which can also be explained by saying 

 that antigens are mixtures in which the proportions of the 

 active substance, always causing the same reaction, are very 

 different. 



The practical suggestion arising from the above would, 

 therefore, be that in order to obtain the maximum curative 

 result with the minimum harmful result, one must search 

 for the proper antigen. 



B. Asthma. Observation 10. M.M.., aged forty-seven years, 

 has suffered for five years from dyspnea which grows worse 

 every year, and shows itself particularly in the evening after 

 sunset, and lasts all night until 10 A.M. or 11 A.M. Cold 

 and rainy days are usually much worse than good weather. 

 Dyspnea is then accompanied by coughing with very difficult 

 expectoration. During and since the war, this condition of 

 asthma has become sensibly aggravated on account of the 

 open air life of the patient who had to dig trenches. 



The patient received in a total period of eighteen days 

 two series of eight hypodermic injections of an autogenous 

 bacterial preparation isolated from his own intestinal flora 



