196 MAN --AN ADAPTIVE MECHANISM 



circle of activity which may ultimately drive the 

 mechanism of the patient to destruction. 



That the sensitizing agent in Graves' disease is the 

 thyroid secretion is made probable by many facts. The 

 administration of thvroid extract alone or of iodin alone 



A. B. 



Section of normal liver of dog. Section of liver of dog after 



injection of iodoform. 



FIG. 45. EFFECT OF IODOFORM ON THE LIVER OF A DOG. 

 Note the extensive vacuolated areas and the disappearance of nuclei in B. 

 (From photomicrographs, X 310.) 



causes all the phenomena of Graves' disease, except ex- 

 ophthalmos and the emotional facies. (Figs. 43, 44, 45.) 

 Moreover, surgical intervention by ligation of the 

 arteries, division of the nerve supply to the gland and 

 the excision of a part of the gland, or therapeutic treat- 



