234 MAN --AN ADAPTIVE MECHANISM 



thyroid secretion upon the foreign protein, but 

 through the action of thyroid secretion upon the lym- 

 phatics, simultaneously with its effect upon the other 

 self-defensive mechanisms. If this be true, there 

 should be less or no lymphocytosis in infection in an 

 individual with myxoedema or in a cretin. Thus, in 

 the immediate symptoms and in the end effects, even 

 to the resulting acidosis and pathologic lesions, we 

 find a close resemblance in the essential phenomena of 

 exertion, emotion, infection and Graves' disease, a fact 

 which tends strongly to uphold the kinetic theory. 



Certain Resemblances between Cardiovascular Disease 

 and Graves' Disease 



The analogy between diseases of the thyroid and 

 diseases involving the adrenals is borne out by many 

 clinical points. Certain cases of Graves' disease and 

 of cardiovascular disease present a particularly strong 

 likeness to each other. Each of these conditions bears 

 an intimate relation to foreign protein activation and 

 to "nervous strain." The etiology of Graves' disease 

 is much the same as that of cardiovascular disease if 

 perhaps in the former case problems of the home be 

 substituted for problems of business. In each of these 

 diseases a recall of the unhappy circumstances or condi- 

 tions which led to or precipitated the acute stage, is suf- 

 ficient to cause an exacerbation of all its symptoms. 

 The most efficient non-surgical means by which each of 

 these diseases may be modified are rest, diversion, 

 change of scene and occupation. In each the secretion 

 of the more closely related gland seems to bear a specific 

 relation to the production of the disease. For instance, 



