BELLADONNA FOLIA 381 



to 0.2 Gm.); of atropine, ^4 to ^{QQ gr. According to Cushney, 

 hyoscyamine is twice as active as atropine in checking secretions and 

 in pupil dilatation. 

 OFFICIAL PREPARATIONS. 



Fluidextractum Belladonnae Radicis, Dose: i to 3 itj> (0.065100.2 mil). 

 Linimentum Belladonnae (95 per cent., with camphor 5 per cent.). 



504. BELLADONNA FOLIA 



The dried leaves of Atropa Belladonna, yielding not less than 0.3 per cent, of total 



alkaloids. 



DESCRIPTION OF DRUG. As they come into market, these leaves are 

 crumpled and broken, of a dull brownish-green tint, the under surface 

 paler than the upper, and with a prominent woody midrib prolonged 

 below into a petiole, margin entire; one of the characteristics is the 

 small, circular holes puncturing the leaves by the dropping off of 

 corky excrescences. This, however, applies, but in a less degree, 

 to the other narcotic leaves. It should be observed that the 

 margins of the three narcotic leaves, belladonna, stramonium, and 

 hyoscyamus, are quite different. 



Powder. Microscopical elements of: See Part iv, Chap. I, B. 



CONSTITUENTS. The alkaloids hyoscyamine and atropine (0.3 to 0.7 per 

 cent.) are present. Belladonnine (oxyatropine) and other alkaloids 

 of less importance exist, with chrysatropic acid. Ash, not exceeding 

 20 per cent. 



ACTION AND USES. Same as the root. Dose: i gr. (0.065 Gm.). The 

 extract is employed in: Pil. Laxative Co. and Pil. Podophyl.,, 

 Bellad. et Capsici, and in the following: 



OFFICIAL PREPARATIONS. 



Tinctura Belladonnae Foliorum (10 



per cent.), ..................... Dose: 5 to 15 ITJJ (0.3 to I mil). 



Extractum Belladonnae Foliorum 



(1.4 per cent, alkaloid) .......... % to % gr. (0.008 to 0.048 Gm.). 



Unguentum Belladonnae ( 10 per cent.) . 



505. MANACA. Portions of the root and stem of Brunf el'sia hopia'na Bentham, 

 a Brazilian plant. Strongly recommended in chronic subacute rheumatism 

 as a powerful alterative. Dose: 15 to 60 gr. (i to 4 Gm.). 



506. SCOPOLA. SCOPOLA, U.S.P. VIII 



The dried rhizome of Scopola Carniolica Jacquin, yielding by former U.S.P. proc- 

 ess not less than 0.5 per cent, of its alkaloids. 



DESCRIPTION OF DRUG. From 25 to 100 mm. (i to 4 in.) long and from 10 to 20 

 mm. (% to % in.) thick, frequently sliced. The upper surface is beset with 

 cup-shaped stem scars; externally, yellowish-brown to dark brown; wrinkled 

 longitudinally, obscurely annulate, rough and nodular; fracture short, show- 



