REMIJIA 



405 



anaemia of the brain, contraction of blood-vessels, etc. Heart action 

 . is depressed. Reflex excitability of the spinal cord is lowered. In 

 the blood, quinine arrests the migration of the white corpuscle and 

 checks its amoeboid movement; the oxygen-carrying function of the 

 red corpuscle is impaired; infectious micro-organisms in the blood 

 and tissues are probably rendered inactive or destroyed. The toxic 

 symptoms produced by quinine and allied salts are spoken of collect- 

 ively as cinchonism, which ordinarily is not allowed to go further 

 than tinnitus aurium. 



Dose of cinchona: 15 to 60 gr. (i to 4 Gm.), in powder, fluidex- 

 tract, or its equivalent in the salts of the alkaloids 

 OFFICIAL PREPARATION. 



Tinctura Cinchonas Composita (10 per 



cent., with bitter orange-peel 8 per 



cent., and serpentaria 2 per cent.), i to 4 fl. dr. (4 to 15 mils). 



533- REMIJIA. CUPREA BARK. The 

 bark of Remij'ia peduncula'ta 

 Triana and of Remijia purdiea'na 



Weddell, resembling cinchona in 

 physical properties and constitu- 

 tion. A copper-red bark from the 

 United States of Colombia, grown 

 at an altitude of from 3000 to 6000 

 feet, usually in flat or curved pieces; 

 odor slight; taste bitter. Quinine 

 is contained in this bark to the 

 amount of 0.5 to 2.5 per cent., but 

 no cinchonidine is found; homo- 

 quinine a compound of quinine 

 and cupreine-|-is also a constituent. 

 Remijia bark is largely imported by 

 manufacturers; it was said that the 

 importations of this bark at one 

 time exceeded in amount the entire 

 importations of all the cinchona 

 barks, by reason of its cheapness 

 for the manufacture of quinine. 

 Cinch onamine, CisI^NzO, is one 

 of the principal products of R. 

 purdieana, the bark from which 

 does not respond to Grahe's test. 



534. CEPHALANTHUS OCCIDEN- 

 TALIS Linne. BUTTON BUSH. 

 POND DOGWOOD. Habitat: United 

 States. (Bark.) Tonic, febrifuge, 

 laxative, and diuretic. It has an 

 indirect action on the lungs, and 

 is much used in consumption, coughs, 

 and colds generally. Dose: 30 to 

 60 gr. (2 to 4 Gm.). 



535. MITCHELLA. SQUAW VINE. 

 PARTRIDGE BERRY. The herb of 

 MitchelTa re'pens Linne, a creep- 

 ing evergreen growing in the woods 

 of this country east of the 



Mississippi. Stern branching, bearing roundish-ovate, entire, evergreen leaves 

 about 12 mm. (V 2 m.) long, sometimes marked with 'white lines ; flowers pale 

 purplish, the ovary ripening into a small, scarlet-red berry. Tonic astringent 



Flo. 233. Cross-section of Cuprea bark. 



