DIPHTHERIA BACILLUS VACCINE 467 



TUBERCULIN DENYS, B.F. BOUILLON FILTRE BOUILLON FILTRATE. 

 This is prepared like old tuberculin without the prolonged heating and con- 

 centration; that is, it is simply a glycerin-broth culture of the tubercle 

 bacillus, passed through a porcelain filter; it contains all the soluble 

 products of the growth of the tubercle bacillus. 



DIXON'S TUBERCLE BACILLI EXTRACT. An extract of tubercle bacilli 

 dissolved in normal saline solution. 



ACNE BACILLUS VACCINE. Prepared from the acne bacillus of Unna 

 and Sabouraud. The acne bacillus is not found in all cases of acne, but in 

 those cases in which the bacillus is found it seems to be the active patho- 

 genic agent and the use of acne vaccine may give good results. In other 

 cases the staphylococcus is responsible for the inflammation and the cor- 

 responding staphylococcus vaccine should be tried. If both organisms 

 are present a mixture of the two vaccines may be indicated, but the use 

 of a ready-prepared mixed vaccine is not rational as a routine treatment. 



COLON BACILLUS VACCINE. Made from the Bacillus coli communis. 

 The colon bacillus in a special strain is the cause of many cases of cystitis 

 and pyelonephritis. The use of an autogenous vaccine is often highly 

 successful in the treatment of these affections. Stock vaccines have not 

 produced good results. If a stock vaccine must be used, it should be 

 polyvalent, so that the special strain needed may be included if possible. 



DIPHTHERIA BACILLUS VACCINE. Made from Bacillus diphtheriae. 

 This vaccine has proved useful in the treatment of diphtheria bacilli 

 carriers as a means of eliminating the bacilli which were resistant to other 

 agents. 



FRIEDLAENDER BACILLUS VACCINE. Made from the Bacillus pneu- 

 moniae, which is found in the nasal secretion or sputum in some nasal or 

 respiratory disorders. 



MICROCOCCUS NEOFORMANS VACCINE. Made from the Micrococcus 

 neoformans, which was isolated from some malignant tumors by Doyen 

 in 1904. 



PYOCYANEUS BACILLUS VACCINE. Made from the bacillus pyocyaneus. 



STAPHYLOCOCCUS VACCINES. Made from the staphylococcus pyogenes 

 aureus, from staphylococcus pyogenes albus, or from the staphylococcus 

 pyogenes citreus or from all three. It is useful in carbunculosis, furuncu- 

 losis, sycosis, and certain cases of acne. An autogenous vaccine is pref- 

 erable, but if this cannot be made, a stock vaccine can be used with good 

 prospect of success. The forms of acne most likely to respond are charac- 

 terized by deep-seated pustules, with considerable induration, situated 

 on the face, chest and back. When the lesions are superficial and indolent, 

 the acne vaccine gives good results, and when there is a mixture of active 

 and indolent lesions, a mixture of the two vaccines is indicated. 



STREPTOCOCCUS VACCINE. Made from different strains of streptococcus 

 pyogens isolated from phlegmon, from the throat, from scarlet fever, 



