

vi PLAGUE INDUCED IN OTHEK RODENTS 135 



Eat Ik, experiment 7, p. 119. 

 Rat 1l, experiment 8, p. 119. 

 Rat lo, experiment 11, p. 121. 

 Rat 1q, experiment 13, p. 121. 

 Rat lR, experiment 14, p. 121. 



Rat Ik. — (1) The bubo showed in the lymph gland haemorrhage, 

 and the blood-vessels generally distended with coagulated blood ; 

 cortical lymph follicles necrotic in many points ; cortical sinuses full 

 of B. pestis ; surrounding lymph vessels either filled with B. pestis 

 or with leucocytes and B. pestis together ; surrounding blood-vessels 

 greatly distended with blood. 



(2) Spleen. — Large blood-vessels filled with coagulated blood; 

 pulp spaces distended by blood ; most Malpighian corpuscles shrunk 

 and small, showing necrosis in one or the other part. B. pestis here 

 and there only in small groups in necrotic parts. 



(3) Liver. — Numerous large blood-vessels distended and filled 

 with coagulated blood ; within the liver lobules and more or less 

 continued from the interlobular vessels were large irregular spaces 

 filled with coagulated blood ; liver cells showed granular degeneration ; 

 B. pestis difficult to find, if any. 



(4) Lung. — General congestion, haemorrhage in some parts ; 

 infundibula and small bronchi filled with leucocytes and fibrin. 

 B. pestis difficult to find, if any. 



(5) Kidney. — Large blood-vessels distended and filled with blood ; 

 glomeruli of Malpighian corpuscles swollen, capillaries containing 

 moderate amount of blood. B. pestis difficult to find, if any. The 

 convoluted tubes appeared in most parts filled with hyaline casts, 

 the lining epithelium fairly well preserved. 



Rat 1l. — (1) Bubo. — Lymph vessels and lymph spaces around 

 the glands injected and distended with B. pestis ; the blood-vessels of 

 the gland itself greatly distended by blood. 



(2) Spleen. — All blood-vessels and blood spaces distended by 

 blood. B. pestis only in small masses and not numerous. 



(3) Liver. — Capillaries of the lobules much distended by blood ; 

 liver cells contained fat globules, and many of them showed granular 

 disintegration. Some capillaries — but not in many places — contained 

 plague bacilli. 



(4) Lung. — Great congestion in all blood-vessels ; haemorrhage in 

 some alveoli. No B. pestis discernible. 



