vii INFECTION OF ANIMALS WITH PLAGUE 161 



swollen and partially necrotic Peyer's patch, the latter 

 itself much injected, but well marked off from the hsemor- 

 rhagic tissue around it ; the mesenteric glands swollen, 

 deep purple in colour, hsemorrhagic. Both testes showed 

 the parenchymatous and superficial lymphatics filled with 

 blood, and the lymphatics of the spermatic cord and pelvic 

 lymph gland were in like condition. 1 The spleen was 

 much enlarged, dark ; both lungs congested ; liver, 

 kidneys, and suprarenals in same condition. 



Film specimens were examined and cultures made — 

 (a) of the mesenteric glands, (b) of the spleen, (c) of the 

 heart's blood. In all these instances the film specimens 

 showed crowds of B. pestis, and the cultures were crowded 

 with colonies of B. pestis in pure state. 



The hsemorrhagic patch of the ileum, and the Peyer's 

 gland, the kidney, liver, spleen, lung, mesenteric gland, 

 and testes were placed in Miiller's fluid, then in spirit. 

 After completion of the hardening process these organs 

 were used for preparing sections. 



Eat No. 2. — The post-mortem examination showed 

 almost exactly the same appearances as those of Eat 1, 

 except that the testes appeared free from any change. The 

 lower ileum showed a hsemorrhagic patch in which there 

 was a swollen, prominent, congested, and partly necrotic 

 Peyer's gland. The spleen, kidneys, mesenteric glands, 

 and lungs were similar to those of Eat 1. 



Film specimens and cultures of the hsemorrhagic 

 mesenteric glands, of the spleen, and of the heart's blood 

 showed that these organs contained crowds of B. pestis. 

 The hsemorrhagic patch and swollen Peyer's gland and 



1 I have seen this condition of the testes occasionally also in guinea-pigs which 

 have succumbed with acute plague after subcutaneous injection. 



M 



