172 ORIENTAL PLAGUE chap. 



Rats Nos. 10 and 11 were fed on June 7 with plague 

 organs dried with rice. These two animals were distinctly 

 affected on June 10, and they were found dead on the 

 morning of June 11. On post-mortem examination the 

 lower ileum in both animals was found intensely inflamed 

 and showed haemorrhages ; the mesenteric glands were 

 swollen and hemorrhagic; spleen typical, large, dark, 

 firm, and crowded with B. pestis. 



Rats Nos. 12 and 13 were fed on June 7 with plague 

 organs dried with wheat. One was found dead in the 

 morning of June 10, the other remained unaffected. The 

 post-mortem examination of the dead rat showed in the 

 ileum five different spots where haemorrhage had taken 

 place over and in the neighbourhood of Peyer's glands ; 

 within the cavity of the ileum was a good deal of blood, 

 and mingled with it crowds of typical B. pestis ; in the 

 mesentery around the mesenteric glands was a big hemor- 

 rhagic patch, while the mesenteric glands themselves were 

 swollen and exhibited petechia. The spleen was large, 

 dark, firm, and crowded with B. pestis ; both kidneys, 

 which were twice the normal size, were deeply congested 

 in all parts; both lungs were congested with numerous 

 hemorrhagic spots. Film specimens and cultures of the 

 intestinal sanguineous contents of the spleen and of the 

 heart's blood yielded B. pestis. Sections were made of 

 the hardened intestine through the hemorrhagic spots, and 

 Figs. 82, 83, 84, and 85 show the appearances observed. 



Fig. 82 is from a transverse section through a hemor- 

 rhagic part of the intestine close to a swollen Peyer's 

 gland ( x 25). In the lumen of the intestine is seen a 

 mass which is only the outlier of a larger mass attached 

 to the inner portion of the Peyer's patch. Part of this 



