vii INFECTION OF ANIMALS WITH PLAGUE 173 



central mass is shown more highly magnified ( x 300) in 

 Fig. 83. Here may be recognised between two masses of 

 wheat A and B — or what is left of wheat undigested — 

 a streak of tissue CC^, which, examined under a higher 

 power, x 1000 (as in Fig. 84), shows itself to be a mass of 

 tissue, most probably a piece of spleen ; and, further, 

 there is seen in this tissue, as also in the part of wheat 

 next to it, at B, continuous masses and clumps of B. pestis 

 which appear dark in the figure. Likewise there is seen 

 in Fig. 83 at G x a dense mass of B. pestis surrounded by 

 what under high power is recognisable as a necrotic portion 

 of tissue, probably spleen. At A in Fig. 83 there are 

 gluten globules and septa between them. Here, then, is 

 demonstration of a striking fact. In the lumen of the 

 intestine, exactly at a hsemorrhagic spot and next an 

 inflamed Peyer's gland, is a piece of the infected food — i.e. 

 plague tissue wedged in between two portions of wheat 

 — which would seem to have become attached to a Peyer's 

 patch during the life of the animal. In this food particle 

 there are recognisable more or less undigested parts of wheat 

 (gluten portions) and part of the original plague organ that 

 was dried with it. Further, it would appear there had 

 been active multiplication of plague bacilli in the adjoining 

 loosened wheat particle. 1 



Fig. 84 shows under a high power these streaks and 

 masses of B. pestis between the layers of the remains of 

 the wheat A A, B being the original plague material 

 dried in the wheat. It remains to be noted that many 

 villi of Fig. 82 showed, when examined with a high power, 

 crowds of B. pestis on the surface (denuded of epithelium) 



1 This observation does not lend support to Hankin's contention that the 

 wheat offers antagonism and inhibition to the life and multiplication of B. pestis 

 brought in contact with it. 



