ON EPIGNATHUS 1 3 



small cubical epithelial cells, resting directly on a well marked muscularis 

 mucosae. No intestinal glands are seen in any of the sections. 



Salivary Gland. — Embedded in the tissue, near the deformed mouth, 

 is an irregular glandular structure about half-an-inch in diameter. This 

 microscopically shows the normal structure of a salivary gland. In the 

 sections numerous alveoli and ducts are seen. Both serous and mucous 

 alveoli are present. The mucous alveoli are not so numerous, but are 

 readily recognisable from thdr clear distended mucous cells. 



Thyroid Gland. — Tissue, containing thyroid gland substance, was 

 found in an indefinite fibrous mass under the skin of the upper part of 

 the tumour. This glandular structure has a tough fibrous capsule i mm. 

 thick, and inside this a yellowish brown material, with here and there a 

 cystic condition. Microscopically, vesicles of thyroid gland are to be 

 made out. The vesicles are mostly elongated, and some are much 

 distended, so that their lining cells are flattened. The smaller vesicles 

 have walls, consisting of a single layer of cubical epithelium-cells, with 

 deeply-stained nuclei. 



Liver Cells. — In the left half of the tumour there is a solid nodule as 

 large as a walnut. This has a smooth surface, and has the colour and 

 consistency of liver. Microscopic sections give no indication of the 

 lobular structure of liver, but show large cells, with the nucleated 

 granular appearance of hepatic cells. Ramifying among these cells are 

 numerous blood capillaries. 



Nervous Tissue. — The lower part of the tumour is made up of an 

 irregular soft mass, covered by the smooth membrane already described. 

 On cutting into this it is seen to consist of a light yellowish material, of 

 very friable consistency. Several pieces of this were embedded, and 

 sections, stained by different methods, examined microscopically. All 

 the sections agree in showing a rudimentary or embryonic nervous tissue. 

 In the sections is seen a nuclear tissue with no cell boundaries, the 

 nuclei lying in a syncytial protoplasm. The nuclei stain very readily, 

 and many are dividing by mitosis. The tissue is similar to embryonic 

 nervous tissue in an early stage of development. 



Although many different parts of the tumour were examined micro- 

 scopically, no nerve fibres, either medullated or non-medullated, were 

 observed. On the right side, some fibres from the great palatine nerve 

 were traced on to the stalk of the tumour, but only for a short distance. 



(187) 



