CONTRIBUTION TO PATHOLOGY OF EXOPHTHALMIC GOITRE 9 



surface of the gland was of a dark pink colour, and presented a granular 

 fleshy appearance. There was no evidence of any increase in size of 

 the parathyroids. 



Microscopic Examination. 



Thyroid Gland. — There was an undoubted increase in the number of 

 alveoli, which were also, as a rule, much smaller than those of the normal 

 gland. Their size, however, varied greatly, and in shape they tended to 



Fig. 4. — Section of Thyroid Gland (Case i). 



Shews the irregularity in shape of the larger alveoli and the papillary projections of the wall. 



Zeiss Obj. A, Oc. 4. 



be oval or irregular. In the case of the larger vesicles, curious papillary 

 projections of the lining membrane were frequently seen. (Figs. 3 and 

 4.) The alveolar epithelium had lost its typical cubical shape, and had 

 assumed a high columnar form (Fig. 5). The cells were stained sharply 

 with the usual staining solutions ; their nuclei were rounded or oval, and 

 stained deeply with logwood. In one or two instances the nuclei shewed 



(207) 



