ON THE ACTION OF CERTAIN BACTERIA II 



B. icteroides, B. bovis morbificans Basenau, the bacillus of intestinal 

 diphtheria of Ribbert, B. psittacosis Nocard, and B. diphtherias colum- 

 barum Loeffler. 



Bacillus suipestifer, Kruse. (Bacillus cholerae suum, Migula). 



The following description is abstracted from the work of Nocard 

 and Leclainche (4). 



In the acute form of the disease necrotic foci are seen in the 

 sub-mucous tissue of the tongue, and consisting of greyish-yellow caseous 

 masses, which may involve the mucous membrane and finally give rise to 

 ulceration — the ulcers being covered with diphtheritic deposits ; the 

 necrosis may extend into the underlying muscles. The tonsils contain 

 hsemorrhagie foci or cheesy nodules. The lesions in the stomach and 

 intestine are variable in their intensity, and consist of an exudative 

 inflammation of the mucous membrane, followed by necrosis of the tissues. 

 Usually the spleen is normal ; in exceptional cases it contains caseous 

 foci. Multiple nodules of necrosed tissue often occur in the liver. 



In the chronic form, caseous broncho-pneumonia is met with in 

 addition to the intestinal lesions. 



Young animals are especially prone to the disease. The bacillus 

 is pathogenic to the guinea-pig, the rabbit, the white and grey mouse, the 

 white rat and the pigeon. 



B. icteroides Sanarelli. — From the researches of Reed and Carrol (5), 

 this organism is closely related to B. suipestifer, and produces identical 

 lesions in guinea-pigs, mice, rabbits and dogs. 



The B. bovis morbificans was isolated by Basenau, in 1893, from the 

 muscles and organs of a cow killed on account of puerperal metritis. 

 In several instances the spleen was enlarged, and greyish-white nodules 

 were found in this organ and in the liver. It is pathogenic by feeding, 

 with symptoms of gastro-enteritis to guinea-pigs, mice, rats and calves, 

 and frequently causes, in inoculated animals, numerous miliary purulent 

 and necrotic foci in the liver and spleen. 



B. psittacosis Nocard. — Lehmann and Neumann state that it is 

 not clear whether this organism should be placed in the hasmorrhagie 

 septicaemia group, though they point out that it has a similarity to 



(297) 



