LEUCOCYTOSIS AND OPSONIC CONTENT OF SERUM 13 



In the following experiment the control animal was inoculated 

 intraperitoneally with 2 cc. of a 5 % solution of carbolic acid {vide 

 Exp. 17):— 



Rabbit VIL 



It will be seen that in this last case a slight relative neutrophilia 

 occurred, but in all the preceding cases the variations in the differential 

 count throughout the day were quite inconsiderable. 



Guinea-pig. 



Much less attention has been paid to the leucocytes of the guinea-pig 

 than to those of the rabbit. 



Hirschfeld (loc. cit.) gave the following classification, but did not 

 record any numerical data : — 



(i) Eosinophiles with large ball-shaped granules. 



(2) Indulinophiles with small ball-shaped granules. 



(3) Polynuclears without granulation (scarce). 



(4) Mast cells. 



(5) Large granulated lymphocytes. 



(6) Small non-granular lymphocytes. 



Hirschfeld's indulinophile cells, whose granules take up the indulin 

 from the eosin-aurantia-indulin mixture, correspond to the pseudo- 

 eosinophile cells of Kurloff, and in function to the poly nuclear cells 

 of man. 



Runoff's (37) classification was as follows : — 



(i) Polynuclear cells with pseudo-eosinophile granulation. 



(2) Typical eosinophile cells. 



(3) Nigrosinophile cells, differing from the true eosinphiles in this 



respect only, that, in the eosin-aurantia-nigrosin mixture, their 

 granules take up the nigrosin tint while the eosinophile 

 granules are red. 



(333) 



