LEUCOCYTOSIS AND OPSONIC CONTENT OF SERUM 



inoculation, and that its duration 



X. 



is always transitory, we made complete 

 blood and opsonic estimations every 

 hour during the first three or four hours. 

 Blood drawn 40 minutes after injec- 

 tion showed practically no change 

 either in the absolute or differential 

 count. Two hours after inoculation, 

 however, the total leucocytes had risen 

 from 8,700 to 14,500, and there was a 

 marked relative neutrophilia. At the 

 third hour the neutrophilia had still 

 further increased, though the total count 

 had slightly fallen. A final estimation 

 at the seventh hour showed that, in the 

 interval, the leucocytes had again 

 mounted upwards to 17,000, while the 

 neutrophilia was well maintained. 

 During the seven hours that the animal 

 was under observation, no change at 

 all took place in the opsonic content of 

 the serum. 



Exp. IX. (Chart IX.) Rabbit. Intra- 

 venous inoculation (4*5 cc). 



Hourly examinations were made 

 after inoculation, but practically no 

 change took place in the blood-picture 

 either in the direction of hyperleu- 

 cocytosis or relative neutrophilia. 



The fluctuations in the opsonic 

 content were also trivial during the 

 period of observation. 



Exp. X. (Chart X.) Guinea-pig. Intra- 

 peritoneal inoculation of 5 cc. of 

 Tallianine. 

 Three hours after inoculation, an 



enormous rise had taken place in 



(341) 



