26 



QUATERCENTENARY STUDIES IN PATHOLOGY 



and there was a fairly well-marked neutrophilia which was maintained at 

 the seventh hour after inoculation. 



During the period of observation no rise took place in the opsonic 

 content. 



4. — Filtrates from autolysed staphylococcus cultures. 



Exp. XVI. (Chart XVI.) Rabbit. Intraperitoneal injection of i cc. of 

 autolysed staphylococcus culture ( = filtrate from 70 million cocci). 



Five hours after injection there was no rise in the total count, but 

 there was a marked relative neutrophilia. At the seventh hour, there was 



XV. 



XVI. 



XVII. 



a slight rise in the total count and a still more marked neutrophilia. At 

 the end of 24 hours, the polynuclears had fallen to a percentage of 42, 

 and at the end of 48 hours they had returned to their initial level. 



Regarding the opsonic content, no change took place in the first five 

 hours, but, at the seventh hour, the opsonic index rose to 17. The high 

 opsonic tide was only of short duration, and had completely disappeared 

 at the end of 24 hours. 



(346) 



