\ 



5*3 

 5*2 



2-5 



2*4 



IMMUNITY IN PNEUMOCOCCAL INFECTIONS 21 



Atkin found that the leucocytes of a lupus patient and those of a normal 

 individual were approximately identical in action. To quote their 

 experiment : — 



I. Serum of a normal individual + T. B. Emulsion + leucocytes of a normal 



individual - - 5*7 



2- " '• + 11 + leucocytes of a lupus 



patient- - - 5*4 



3- " •• + „ + „ „ 



4- " " + ri + „ „ 



5. Serum of a lupus patient + T. B. Emulsion + leucocytes of a normal 



individual 



6. It II + „ 4. „ „ 



7- " n + II + II M 3*2 



I have determined the behaviour of the leucocytes in acute croupous 

 pneumonia, a disease in which there is pronounced changes in the 

 number of leucocytes at the different periods. 



Serum of Normal individual + Pneumococci + normal leucocytes - - 13*2 



Serum of Pneumonia patient No. i + Pneumococci + normal leucocytes 6*5 



Serum of Pneumonia patient No. 2+ m + m 9-7 



Normal serum + Pneumococci + leucocytes of Pneumonia patient No. i 9*5 



Normal serum + n + n n No. 2 8*4 



From these results it would appear, at first glance, that the leucocytes 

 were not so indifferent, and that the leucocytes of a pneumonia patient 

 were not capable of taking up so many cocci in the same period of time. 

 But the number of leucocytes in the experiments was here variable, for, 

 in the normal blood, on the day in which the experiment was performed, 

 there were 8,200 leucocytes per cm.m., in pneumonia patient No. i, 18,000, 

 and in No. 2, 19,200. Many more leucocytes were present, and actively 

 phagocytic, in the last two cases. 



Total in 

 50 leucocytes. 



Normal serum + Normal leucocytes + Pneumococci . - - - 660 

 !i + Leucocytes of Pneumonia patient No. i 4- Pneumococci 475 



It + M II No. 2+ II 420 



But if numbers in proportion to the number of polymorphonuclears of 

 patients with pneumonia were taken, the results show that the poly- 



(385) A A 



