ON ANTI-IMMUNE-BODIES 115 



SUMMARY OF RESULTS OBTAINED BY H^EMOLYTIC 

 METHODS 



1 . The anti-immune-body obtained by injecting the normal 

 serum of the rabbit has been shown to act on two immune- 

 bodies produced in the rabbit by active immunization, and 

 the corresponding anti-immune-body obtained by injecting 

 guinea-pig's serum was shown to act on two natural immune- 

 bodies in the serum of that animal. 



2. The anti-immune-body is shown by quantitative 

 experiments not to interfere in any way with the combination 

 of immune-body with the receptors of the red corpuscles. 



3. The anti-immune-body combines with red corpuscles 

 treated with immune-body (sensitized corpuscles) and inter- 

 feres with the combination of complement. Lysis may thus 

 be prevented by the anti-immune-body ; but where this 

 is not the case it is shown by quantitative methods that a 

 certain amount of complement is kept out of combination. 



4. The natural immune-bodies of the serum injected 

 combine directly with the anti-immune-body developed, 

 and have also the power of dissociating anti-immune-body 

 after it has combined with immune-body fixed to red 

 corpuscles. The combination of anti-immune-body is a 

 comparatively weak one and belongs to the group of rever- 

 sible actions. 



5. We have been unable so far to demonstrate that the 

 previous combination of complement prevents the union of 

 anti-immune-body with red corpuscles treated with immune- 

 body. 



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