40 THE INTERNAL SECRETIONS 1920 



We must bear this in mind whenever we desire to 

 institute organotherapy, and see that the patient is 

 supplied with all those principles of internal secretion 

 that his organism possibly may be in need of. 



It is to be hoped that the advances in physiological 

 chemistry will provide us in the near future with cer- 

 tain means for the detection of the different principles 

 of the internal secretions in the blood, for they must 

 absolutely be in order to exert their influence on the 

 organism. At that time we will also be able to diag- 

 nose precisely which particular gland is causing the 

 trouble in a given case, as its comparative hypo- or 

 hyper-activity, for then we shall be able to demonstrate 

 its dysfunction in a scientific manner by determining a 

 decreased or increased amount of its active principle 

 in the blood. But until this is possible, we must have 

 recourse to the method known as pluriglandular the- 

 rapy in order to give the organism a chance to select 

 and make use of what may be lacking. 



Occasionally we find cases where the deficiency of a 

 certain single gland is well manifested, and in such 

 instances monoglandular therapy directed to the one 

 gland in question largely fulfills the indication. 



The following cases, some of them still under my ob- 

 servation, have convinced me of the efficacy of the 

 glands of internal secretion as therapeutic measures in 

 certain instances. 



CASE No. 1. A young man of 26, fairly well developed 

 physically, and a butcher by occupation, consulted me 

 for extreme weakness. About 2 P. M. he said he is all 

 played out, although he never works very hard. His 

 family history and past medical history are negative. 

 The physical examination revealed nothing abnormal 

 except that his blood pressure was remarkably low for 

 his age, the systolic pressure being 100 mm. and the 

 diastolic only 55 mm. 



On the assumption that the patient was not getting 

 enough of the adrenal secretion, the dried adrenal 



