12 THE INTERNAL SECRETIONS 1920 



cult and painful menstruation, with the accompanying 

 back and headache; hysteria; melancholia; neuras- 

 thenia are symptoms with which we all are familiar. 



From time immemorial we physicians have been 

 treating those patients by giving sedative, tonic, and 

 digestive drugs, also operations, electricity, baths, mas- 

 sage and suggestion with little or no success at all. 



Now, it is in the treatment of just such cases that I 

 have had the most successful results with the glandular 

 extracts. I dare say you could hardly find a physician 

 who is not familiar with the action of adrenalin or who 

 has not witnessed the immediate and powerful specific 

 effect of pituitrin on the uterus at the obstetric bed. 

 Yet, there are some doctors who doubt the efficacy of 

 the other organic extracts. They also doubt the effi- 

 cacy of those two in so far as being remedial in the 

 treatment of disease. However, the number of the 

 doubters is rapidly declining. Those who remain are 

 of two classes : Those who have never had any experi- 

 ence with organotherapy, who have not given the mat- 

 ter any deep thought; and those who have used only 

 the monoglandular extracts, losing sight of the fact 

 that the endocrine glands are so closely interrelated 

 that a monoglandular dysfunction is, perhaps, a physio- 

 logical impossibility. 



I report in detail the following case as being typical 

 of endocrine dysfunction, and evidence of the results 

 of pluriglandular treatment. No doubt the condition 

 of this poor woman can be paralleled many times by 

 any physician of a few years* experience, especially 

 those giving attention to chronic ills: 



Mrs. R. F. W., age 36, mother of three children, 

 youngest three years. No abortions. Family history 

 good. Personal history good until beginning of present 

 illness. 



Present illness began in November, 1918, closely fol- 

 lowing influenza. In so far as the special symptoms of 

 influenza were concerned she soon recovered, but soon 

 noticed that her digestion was not normal. She would 



