158 THE INTERNAL SECRETIONS 1920 



shown that emotions such as fear, anger, grief in fact, 

 any strong emotional excitement will stimulate the 

 adrenals, and further, that if the stimulus is continued 

 over a period of time, the stimulation gives way and 

 depression follows. This, in fact, applies to all stimu- 

 lants. 



The observations of Kaplan (13) on changes in the 

 formation and position of the teeth in relation to the 

 internal secretory apparatus are indeed interesting and 

 exceedingly helpful in deciding whether a given case is 

 really congenital or only an acquired hypofunction. 

 This, I believe, is vitally necessary in order that we may 

 have some mental concept of the results we expect to 

 attain by organotherapeutic measures. My own ob- 

 servations agree with Kaplan (13) , i. e., that blunt, flat 

 upper cuspids, the so-called eyeteeth, are an indication 

 of slow-acting adrenals. 



We can get the internal secretory mechanism of the 

 inherited case to working more normally by gland feed- 

 ing, but the slightest little mishap will throw the whole 

 thing out of balance again, whereas, in the acquired 

 case, our treatment is more prompt and decisive in ac- 

 tion, and the results of much longer duration. To lend 

 emphasis let us contrast the following cases : 



Mrs. H. J. G., age 27, left Wisconsin in 1908 because 

 of asthma, came to Southern California and asthma 

 disappeared immediately on arrival in Los Angeles. 

 She remained free for three years, when in 1911 an at- 

 tack of appendicitis occurred. This was followed by a 

 recurrence of the asthma, which continued to Decem- 

 ber, 1916, when I first saw her. Upon examination, I 

 decided she was suffering from hypocrinism or hypo- 

 function of the pituitary, thyroid, adrenal and ovarian 

 glands. Incidentally, it is interesting to note that her 

 mother, at this time, also showed evidence of pituitary, 

 thyroid and adrenal hypofunction. A combination of 

 pituitary, thyroid, adrenal and ovarian glands was 



