XVII 



INVESTIGATIONS OF SOME BIOLOGICAL 

 EFFECTS OF ADRENALIN 



BY DR. LEON BINET, Paris, France 



The work that we have the honor of addressing to 

 "THE HARROWER LABORATORY" is the result not 

 of documents sought for in medical literature, but of 

 personal investigation, made in various laboratories 

 with the assistance or under the direction of our mas- 

 ters, Professors Ch. Achard, H. Richet and H. Roger. 

 These inquiries are related to : 



1. The action of adrenalin on carbohydrate meta- 

 bolism. 



2. The action on the heart. 



3. The action on shiver (tremor) . 



4. Its action in anesthesia. 



5. Its action on tetany. 



The bibliography which follows them is a complete 

 list of the publications in which some of these inquiries 

 have been expounded. 



THE ACTION OF ADRENALIN ON CARBOHYDRATE 

 METABOLISM 



It is now known, since the publication of the work 

 of Blum, Zuelzer and Metzger, that the injection of 

 adrenalin, either under the skin or into the veins brings 

 about glycosuria, and it is proved that this glycosuria is 

 connected with an increase of sugar in the blood. This 



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