180 THE INTERNAL SECRETIONS 1920 



THE ACTION OF ADRENALIN ON TETANY 



We know that the dog which has been deprived of 

 the parathyroid has motor troubles, shown by attacks 

 of tetany; and respiratory troubles, shown by periods 

 of polypnea these troubles coming on as a result of 

 various causes. Our experiments have shown us that 

 the injection of 0.5 mg., or 1 mg. of adrenalin in a dog 

 deprived of the parathyroid is followed, 



First, by an attack of tetany, beginning some seconds 

 after the injection, reaching its maximum half a min- 

 ute after and composed of convulsions and muscular 

 contractions ; 



Second, by a period of polypnea, following the 

 tetany, connected with an increase in the bodily temper- 

 ature (404) , as well as with no increase at all. 



Such experiments show that adrenalin must not be 

 used in cases of tetany. 



BIBLIOGRAPHY 



Achard (C.) & Desbouis (G.) : Recherches sur 1'util- 

 isation des sucres a Ptat pathologique, Arch, de 

 mid. exper. et d'anat. path. (Paris), 1914, xxvi, 

 105. 



Id.: L'insuffisance glycolytique provoqu6e par 1'extrait 

 d'hypophyse et par I'adr&ialine, C. r. Soc. Biol. 

 (Paris), 1913, Ixxiv, 467. 



Achard (C.), Ribot (A.) & Binet (L.) : Action des 

 extraits d'organes sur 1'hyperglycemie provoquee, 

 ibid., 1919, Ixxxii, 775; L'epreuve de 1'hypergly- 

 c6mie provoquSe dans les alterations pancrSatiques 

 experimentales, ibid., 1919, Ixxxii, 788. 



Binet (L.) : L'action de l'adrnaline sur Tappareil 

 cardiovasculaire, Presse med. (Paris), 1917, xxv, 

 191; L'action de Padrenaline sur le tube gastroin- 

 testinal, ibid., 1918, xxvi, 407; Recherches sur le 

 tremblement, These de Paris, 1918, p. 103. 



Dclbet (P.), Herrenschmidt (A.) & Beauvy (A.): 

 Chloroformisation et les capsules surrenales, Rev. 

 de chir. (Paris), 1912, xlv, 544. 



