250 THE INTERNAL SECRETIONS 1920 



physical findings were negative througnout, except for 

 a slight hypertrophy of the prostate. There was a defi- 

 nite mental obsession due to anxiety over his condition. 

 After receiving ten injections of the serum the patient 

 had improved greatly and had resumed business. His 

 nights were comfortable, and he felt much improved. 

 Three months after beginning treatment he gained 

 back the power of erection and ejaculation. Micro- 

 scopical examination of the semen, however, revealed 

 the fact that the spermatozoa were not motile. The 

 psychological stimulus coincident to the return of the 

 function was indeed wonderful in that it changed the 

 mental aspect entirely, allowing him to dispel the 

 pseudo-obsession under which he was laboring. This 

 patient is well and working eight hours every day. 

 His mental attitude is cheery, and he looks and acts 

 twenty years younger. 



CASE V. Capitalist, aged fifty-four, past history 

 negative as to medical and surgical illness. Has always 

 indulged in alcohol to excess. History of sexual indis- 

 cretion dates back for the past twenty years. Con- 

 sulted me June, 1919, because of inability to maintain 

 erection, with partial loss of ejaculative powers. This 

 condition had been present for a year. Physical find- 

 ings negative aside from hypertrophied prostate. Ad- 

 ministration of serum commenced June 15, 1919. Re- 

 ceived ten injections in all. On discharge function had 

 returned. I may state that there was no medication 

 aside from the serum used in this case. This patient 

 was of the roue" type and the condition was the result 

 of fatigue of the endocrine secretion which responded 

 to specific stimulation in the form of activating sub- 

 stances. 



CONCLUSION 



In none of these cases was there any evidence of dis- 

 ease of the interstitial cells of Leydig. In each case 

 electric stimulation caused a slight erection of the 

 penile musculature, with a short contraction of the 

 sphincter muscle. The patient in Case II did not react 

 in any way to large doses of strychnine, which led me 

 to believe that neurological conditions existed. In 



