STERILITY AND THE ENDOCRINES 251 



spite of this fact endocrine stimulation produced re- 

 sults. Last but not least, the psychological effect pro- 

 duced by the renewing or revitalizing of a dormant 

 function was capable in these five cases of so changing 

 the outlook on life that bodily vigor and mental activity 

 were substituted for morbid forebodings. 



The question of grafting or implanting testes is a 

 satisfactory procedure in the majority of cases, but as 

 sex dysfunction is pluriglandular in its entirety, it is 

 necessary to ascertain the metabolic rate and function 

 quotient of the other secretory glands before operative 

 procedure is advised. In a testicular implant case in 

 which operation was performed some time ago, it was 

 necessary to resort to thyroid feeding after the implan- 

 tation in order to co-ordinate the vis a tergo of the 

 secretory equilibrium,, the patient being myxedematous 

 as well as suffering from hypogonadism. 



I am now working with a solution composed of the 

 salts of the blood, the concentration being isotonic with 

 the blood serum, into which the gland of the donor is 

 placed to facilitate its state of resistance, during the 

 interim between removal and implantation. By this 

 method the functioning power of the gland may be kept 

 in a highly nourished state. The spermatogenic func- 

 tion of the testes is not endogenous, but pluriglandular 

 in its sequence. In other words, sex dysfunction, or 

 testicular dysfunction, is hypoendocrinism, rather than 

 hypogonadism. 



